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Registro Completo |
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Biblioteca(s): |
Embrapa Gado de Leite. |
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Data corrente: |
28/04/2010 |
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Data da última atualização: |
09/08/2022 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
NASCIMENTO, E. M.; FURLONG, J.; PIMENTA, D. S.; PRATA, M. C. de A. |
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Afiliação: |
ÉRICA MARIA NASCIMENTO, UFJF; JOHN FURLONG, CNPGL; DANIEL SALES PIMENTA, UFJF; MARCIA CRISTINA DE AZEVEDO PRATA, CNPGL. |
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Título: |
Efeito anti-helmíntico do hidrolato de Mentha villosa Huds. (Lamiaceae) em nematóides gastrintestinais de bovinos. |
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Ano de publicação: |
2009 |
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Fonte/Imprenta: |
Ciência Rural, Santa Maria, v. 39, n. 3, p. 817-824, 2009. |
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Idioma: |
Português |
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Conteúdo: |
RESUMO - Atualmente, o estudo da atividade anti-helmíntica de plantas medicinais em ruminantes tem atraído bastante interesse. Mentha villosa Huds. (Lamiaceae) é uma das espécies de hortelã que tem sido utilizada popularmente devido às diversas propriedades medicinais, inclusive para o controle de verminoses. O presente estudo teve como objetivo testar a atividade anti-helmíntica do hidrolato dessa planta em bezerras infectadas por nematóides gastrintestinais, tanto in vitro, pelo método de coprocultura quantitativa, quanto in vivo, por meio do teste de redução no número de ovos de nematóides nas fezes dos hospedeiros. No teste in vitro, o hidrolato nas concentrações de 40%, 60% e 80% e 100% apresentou porcentagem de eficácia de 91,88%, 94,15%, 98,40% e 100%, respectivamente, mostrando atividade ovicida significativa sobre nematóides gastrintestinais em bezerras. Entretanto, os resultados do teste in vivo mostraram ausência de atividade anti-helmíntica do hidrolato de M. villosa na dose de 0,1ml kg dia-1, nos animais tratados. ABSTRACT - Currently, it has been of great interest to study the anthelmintic activity of medicinal plants in ruminants. Mentha villosa Huds. (Lamiaceae) is one of the mint species that has been popularly used based on various medicinal properties, even for the control of nematode infections. This study aimed to test the anthelmintic activity of hidrolact of this plant, both in vitro, by the quantitative coproculture method, and in vivo, in calves infected with gastrointestinal nematodes, through the egg count reduction test in feces of the hosts. In in vitro tests, the hidrolact at the concentrations 40%, 60% and 80% and 100% obtained percentage of effectiveness of 91.88%, 94.15%, 98.40% and 100% respectively, showing significant ovicidal activity against gastrointestinal nematodes in calves. However, the hidrolact of M. villosa showed no in vivo anthelmintic activity at 0.1ml kg-1 day-1 on the treated animals. MenosRESUMO - Atualmente, o estudo da atividade anti-helmíntica de plantas medicinais em ruminantes tem atraído bastante interesse. Mentha villosa Huds. (Lamiaceae) é uma das espécies de hortelã que tem sido utilizada popularmente devido às diversas propriedades medicinais, inclusive para o controle de verminoses. O presente estudo teve como objetivo testar a atividade anti-helmíntica do hidrolato dessa planta em bezerras infectadas por nematóides gastrintestinais, tanto in vitro, pelo método de coprocultura quantitativa, quanto in vivo, por meio do teste de redução no número de ovos de nematóides nas fezes dos hospedeiros. No teste in vitro, o hidrolato nas concentrações de 40%, 60% e 80% e 100% apresentou porcentagem de eficácia de 91,88%, 94,15%, 98,40% e 100%, respectivamente, mostrando atividade ovicida significativa sobre nematóides gastrintestinais em bezerras. Entretanto, os resultados do teste in vivo mostraram ausência de atividade anti-helmíntica do hidrolato de M. villosa na dose de 0,1ml kg dia-1, nos animais tratados. ABSTRACT - Currently, it has been of great interest to study the anthelmintic activity of medicinal plants in ruminants. Mentha villosa Huds. (Lamiaceae) is one of the mint species that has been popularly used based on various medicinal properties, even for the control of nematode infections. This study aimed to test the anthelmintic activity of hidrolact of this plant, both in vitro, by the quantitative coproculture method, and in vivo, in calves infe... Mostrar Tudo |
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Palavras-Chave: |
Hortelã. |
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Thesagro: |
Fitoterapia; Planta Medicinal. |
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Categoria do assunto: |
F Plantas e Produtos de Origem Vegetal |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/doc/747943/1/Efeito-anti-helmintico-do-hidrolato-de-Mentha-villosa-Huds.-em-nematoides-gastrointestinais-de-bovinos.pdf
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Marc: |
LEADER 02593naa a2200193 a 4500
001 1747943
005 2022-08-09
008 2009 bl uuuu u00u1 u #d
100 1 $aNASCIMENTO, E. M.
245 $aEfeito anti-helmíntico do hidrolato de Mentha villosa Huds. (Lamiaceae) em nematóides gastrintestinais de bovinos.$h[electronic resource]
260 $c2009
520 $aRESUMO - Atualmente, o estudo da atividade anti-helmíntica de plantas medicinais em ruminantes tem atraído bastante interesse. Mentha villosa Huds. (Lamiaceae) é uma das espécies de hortelã que tem sido utilizada popularmente devido às diversas propriedades medicinais, inclusive para o controle de verminoses. O presente estudo teve como objetivo testar a atividade anti-helmíntica do hidrolato dessa planta em bezerras infectadas por nematóides gastrintestinais, tanto in vitro, pelo método de coprocultura quantitativa, quanto in vivo, por meio do teste de redução no número de ovos de nematóides nas fezes dos hospedeiros. No teste in vitro, o hidrolato nas concentrações de 40%, 60% e 80% e 100% apresentou porcentagem de eficácia de 91,88%, 94,15%, 98,40% e 100%, respectivamente, mostrando atividade ovicida significativa sobre nematóides gastrintestinais em bezerras. Entretanto, os resultados do teste in vivo mostraram ausência de atividade anti-helmíntica do hidrolato de M. villosa na dose de 0,1ml kg dia-1, nos animais tratados. ABSTRACT - Currently, it has been of great interest to study the anthelmintic activity of medicinal plants in ruminants. Mentha villosa Huds. (Lamiaceae) is one of the mint species that has been popularly used based on various medicinal properties, even for the control of nematode infections. This study aimed to test the anthelmintic activity of hidrolact of this plant, both in vitro, by the quantitative coproculture method, and in vivo, in calves infected with gastrointestinal nematodes, through the egg count reduction test in feces of the hosts. In in vitro tests, the hidrolact at the concentrations 40%, 60% and 80% and 100% obtained percentage of effectiveness of 91.88%, 94.15%, 98.40% and 100% respectively, showing significant ovicidal activity against gastrointestinal nematodes in calves. However, the hidrolact of M. villosa showed no in vivo anthelmintic activity at 0.1ml kg-1 day-1 on the treated animals.
650 $aFitoterapia
650 $aPlanta Medicinal
653 $aHortelã
700 1 $aFURLONG, J.
700 1 $aPIMENTA, D. S.
700 1 $aPRATA, M. C. de A.
773 $tCiência Rural, Santa Maria$gv. 39, n. 3, p. 817-824, 2009.
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Registro original: |
Embrapa Gado de Leite (CNPGL) |
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Biblioteca |
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Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
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URL |
Voltar
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Registro Completo
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Biblioteca(s): |
Embrapa Pecuária Sudeste. |
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Data corrente: |
19/02/2019 |
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Data da última atualização: |
19/02/2019 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 1 |
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Autoria: |
GONÇALVES, T. M.; REGITANO, L. C. de A.; KOLTES, J. E.; CESAR, A. S. M.; ANDRADE, S. C. da S.; MOURAO, G. B.; GASPARIN, G.; MOREIRA, G. C. M.; FRITZ-WATERS, E.; REECY, J. M.; COUTINHO, L. L. |
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Afiliação: |
Tássia Mangetti Gonçalves, USP; LUCIANA CORREIA DE ALMEIDA REGITANO, CPPSE; James E. Koltes, Iowa State University; Aline Silva Mello Cesar, USP; Sónia Cristina da Silva Andrade, USP; Gerson Barreto Mourão, USP; Gustavo Gasparin, USP; Gabriel Costa Monteiro Moreira, USP; Elyn Fritz-Waters, Iowa State University; James M. Reecy, Iowa State University; Luiz Lehmann Coutinho, USP. |
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Título: |
Gene co-expression analysis indicates potential pathways and regulators of beef tenderness in Nellore cattle. |
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Ano de publicação: |
2018 |
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Fonte/Imprenta: |
Frontiers in Genetics, v.9, n. 441, p. 1-18, 2018. |
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Idioma: |
Inglês |
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Conteúdo: |
Beef tenderness, a complex trait affected by many factors, is economically important to beef quality, industry, and consumer?s palatability. In this study, RNA-Seq was used in network analysis to better understand the biological processes that lead to differences in beef tenderness. Skeletal muscle transcriptional profiles from 24 Nellore steers, selected by extreme estimated breeding values (EBVs) for shear force after 14 days of aging, were analyzed and 22 differentially expressed transcripts were identified. Among these were genes encoding ribosomal proteins, glutathione transporter ATP-binding cassette, sub-family C (CFTR/MRP), member 4 (ABCC4), and synaptotagmin IV (SYT4). Complementary co-expression analyses using Partial Correlation with Information Theory (PCIT), Phenotypic Impact Factor (PIF) and the Regulatory Impact Factor (RIF) methods identified candidate regulators and related pathways. The PCIT analysis identified ubiquitin specific peptidase 2 (USP2), growth factor receptor-bound protein 10 (GBR10), anoctamin 1 (ANO1), and transmembrane BAX inhibitor motif containing 4 (TMBIM4) as the most differentially hubbed (DH) transcripts. The transcripts that had a significant correlation with USP2, GBR10, ANO1, and TMBIM4 enriched for proteasome KEGG pathway. RIF analysis identified microRNAs as candidate regulators of variation in tenderness, including bta-mir-133a-2 and bta-mir-22. Both microRNAs have target genes present in the calcium signaling pathway and apoptosis. PIF analysis identified myoglobin (MB), enolase 3 (ENO3), and carbonic anhydrase 3 (CA3) as potentially having fundamental roles in tenderness. Pathways identified in our study impacted in beef tenderness included: calcium signaling, apoptosis, and proteolysis. These findings underscore some of the complex molecular mechanisms that control beef tenderness in Nellore cattle. MenosBeef tenderness, a complex trait affected by many factors, is economically important to beef quality, industry, and consumer?s palatability. In this study, RNA-Seq was used in network analysis to better understand the biological processes that lead to differences in beef tenderness. Skeletal muscle transcriptional profiles from 24 Nellore steers, selected by extreme estimated breeding values (EBVs) for shear force after 14 days of aging, were analyzed and 22 differentially expressed transcripts were identified. Among these were genes encoding ribosomal proteins, glutathione transporter ATP-binding cassette, sub-family C (CFTR/MRP), member 4 (ABCC4), and synaptotagmin IV (SYT4). Complementary co-expression analyses using Partial Correlation with Information Theory (PCIT), Phenotypic Impact Factor (PIF) and the Regulatory Impact Factor (RIF) methods identified candidate regulators and related pathways. The PCIT analysis identified ubiquitin specific peptidase 2 (USP2), growth factor receptor-bound protein 10 (GBR10), anoctamin 1 (ANO1), and transmembrane BAX inhibitor motif containing 4 (TMBIM4) as the most differentially hubbed (DH) transcripts. The transcripts that had a significant correlation with USP2, GBR10, ANO1, and TMBIM4 enriched for proteasome KEGG pathway. RIF analysis identified microRNAs as candidate regulators of variation in tenderness, including bta-mir-133a-2 and bta-mir-22. Both microRNAs have target genes present in the calcium signaling pathway and apoptos... Mostrar Tudo |
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Palavras-Chave: |
Maciez da carne; Qualidade da carne. |
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Thesagro: |
Carne; Gado de Corte. |
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Thesaurus NAL: |
Beef; Beef cattle; Beef quality. |
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Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/193047/1/8-GeneCo-expressionAnalysis.pdf
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Marc: |
LEADER 02810naa a2200325 a 4500
001 2106256
005 2019-02-19
008 2018 bl uuuu u00u1 u #d
100 1 $aGONÇALVES, T. M.
245 $aGene co-expression analysis indicates potential pathways and regulators of beef tenderness in Nellore cattle.$h[electronic resource]
260 $c2018
520 $aBeef tenderness, a complex trait affected by many factors, is economically important to beef quality, industry, and consumer?s palatability. In this study, RNA-Seq was used in network analysis to better understand the biological processes that lead to differences in beef tenderness. Skeletal muscle transcriptional profiles from 24 Nellore steers, selected by extreme estimated breeding values (EBVs) for shear force after 14 days of aging, were analyzed and 22 differentially expressed transcripts were identified. Among these were genes encoding ribosomal proteins, glutathione transporter ATP-binding cassette, sub-family C (CFTR/MRP), member 4 (ABCC4), and synaptotagmin IV (SYT4). Complementary co-expression analyses using Partial Correlation with Information Theory (PCIT), Phenotypic Impact Factor (PIF) and the Regulatory Impact Factor (RIF) methods identified candidate regulators and related pathways. The PCIT analysis identified ubiquitin specific peptidase 2 (USP2), growth factor receptor-bound protein 10 (GBR10), anoctamin 1 (ANO1), and transmembrane BAX inhibitor motif containing 4 (TMBIM4) as the most differentially hubbed (DH) transcripts. The transcripts that had a significant correlation with USP2, GBR10, ANO1, and TMBIM4 enriched for proteasome KEGG pathway. RIF analysis identified microRNAs as candidate regulators of variation in tenderness, including bta-mir-133a-2 and bta-mir-22. Both microRNAs have target genes present in the calcium signaling pathway and apoptosis. PIF analysis identified myoglobin (MB), enolase 3 (ENO3), and carbonic anhydrase 3 (CA3) as potentially having fundamental roles in tenderness. Pathways identified in our study impacted in beef tenderness included: calcium signaling, apoptosis, and proteolysis. These findings underscore some of the complex molecular mechanisms that control beef tenderness in Nellore cattle.
650 $aBeef
650 $aBeef cattle
650 $aBeef quality
650 $aCarne
650 $aGado de Corte
653 $aMaciez da carne
653 $aQualidade da carne
700 1 $aREGITANO, L. C. de A.
700 1 $aKOLTES, J. E.
700 1 $aCESAR, A. S. M.
700 1 $aANDRADE, S. C. da S.
700 1 $aMOURAO, G. B.
700 1 $aGASPARIN, G.
700 1 $aMOREIRA, G. C. M.
700 1 $aFRITZ-WATERS, E.
700 1 $aREECY, J. M.
700 1 $aCOUTINHO, L. L.
773 $tFrontiers in Genetics$gv.9, n. 441, p. 1-18, 2018.
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Embrapa Pecuária Sudeste (CPPSE) |
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